Particle formation

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United States of America Patent

SERIAL NO

11416641

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Method for preparing a target substance in particulate form, comprising introducing into a particle formation vessel, through separate first and second fluid inlets respectively, (a) a 'target solution/suspension' of the substance in a fluid vehicle and (b) a compressed fluid anti-solvent, and allowing the anti-solvent to extract the vehicle so as to form particles of the substance, wherein the anti-solvent fluid has a sonic, near-sonic or supersonic velocity as it enters the vessel, and wherein the anti-solvent and the target solution/suspension enter the vessel at different locations and meet downstream (in the direction of anti-solvent flow) of the second fluid inlet. Also provided is apparatus for use in such a method.

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Patent Owner(s)

Patent OwnerAddress
NEKTAR THERAPEUTICS UK LIMITEDBRADFORD WEST YORKSHIRE BD7 1HR

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gilbert, Darren Bradford, GB 3 34
Kordikowski, Andreas Sant Cugat del Velles, ES 21 91
Palakodaty, Srinivas Foster City, CA 6 69

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