Methods for treating diseases or conditions with peptide constructs
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United States of America Patent
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Issued Date -
Jan 4, 2007
app pub date -
Jan 23, 2003
filing date -
Jan 23, 2002
priority date (Note) -
Abandoned
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Abstract
This invention relates to peptides directing a CD4 related T helper cell response wherein the peptides may be used as an adjuvant provided with an antigen or as an immunomodulatory agent without an antigen and compositions comprising modification of a fifteen-mer peptide sequence from the MHC II.beta. chain at positions 135-149 known as Peptide G or a derivative of derG or other derivatives wherein the derivatives enhance the immune response of antigens and methods for treating cancer, autoimmune disease, transplant conditions, infectious conditions or allergies caused by foreign eukaryotic organisms, and infectious conditions or allergies caused by prokaryotic organisms or nonliving agents such as viruses, phages and prions with polypeptides.
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