Assay for ALS and ALS-like disorders
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United States of America Patent
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Issued Date -
Jan 25, 2007
app pub date -
Jul 17, 2006
filing date -
Jul 21, 2005
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The invention relates to an assay for discriminating between amyotrophic lateral sclerosis (ALS) patients and patients with ALS-like disorders that express symptoms like ALS. The method is based on the use of 2-dimensional (2D) gel electrophoresis to separate the complex mixture of proteins found in blood serum, the quantitation of a group of identified biomarkers, and the biostatistical analysis of the concentration of the identified biomarkers to differentiate patients having ALS from patients having other ALS-like disorders.
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