Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid
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United States of America Patent
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app pub date -
Jun 30, 2006
filing date -
Dec 31, 2003
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
An inhalable formulation containing SAE-CD and corticosteroid is provided. The formulation is adapted for administration to a subject by nebulization with any known nebulizer. The formulation can be included in a kit. The formulation is administered as an aqueous solution, however, it can be stored as a dry powder, ready-to-use solution, or concentrated composition. The formulation is employed in an improved nebulization system for administering corticosteroid by inhalation. SAE-CD present in the formulation significantly enhances the chemical stability of budesonide. A method of administering the formulation by inhalation is provided. The formulation can also be administered by conventional nasal delivery apparatus.
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