Selective Dehybridization using Electrochemically-Generated Reagent on an Electrode Microarray
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
Feb 15, 2007
app pub date -
Aug 9, 2005
filing date -
Aug 9, 2005
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The present invention provides a method for selective dehybridization by electrochemically-generated (ECG) reagent on an electrode microarray. The ECG reagent is generated by activation of selected electrodes. Activation alters pH in the vicinity of only the selected electrodes. In one embodiment, the increase or decrease in pH is sufficient to cause dehybridization of an oligonucleotide duplex at the selected electrodes. In another embodiment, the increase or decrease in pH is sufficient to prevent chemical dehybridization at the selected electrodes. The dehybridized single stranded target oligonucleotide may be recovered and amplified by PCR.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully