Nucleotide sequence for assessing transmissible spongiform encephalopathies
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United States of America Patent
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Issued Date -
Feb 22, 2007
app pub date -
Jul 28, 2006
filing date -
Aug 2, 2005
priority date (Note) -
Abandoned
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Abstract
The present invention is directed to the assessment of transmissible spongiform encephalopathy (TSE) using a sample from a living individual. The assessment is based on the use of an RNA marker molecule in a sample of whole blood. The RNA encodes a hypothetical cystein protease. The invention is further directed to the detection of the marker molecule by means of real-time PCR. The invention provides the use of the nucleotide sequence as a marker in the assessment of TSE, a method for assessing bovine spongiform encephalopathy (BSE) in a bovine animal as well as kits to practice the invention.
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