NOVEL SUBSTITUTED DIAMINE DERIVATIVES USEFUL AS MOTILIN AGONISTS

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United States of America Patent

APP PUB NO 20070054888A1
SERIAL NO

11555914

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to novel substituted diamine derivatives for the formula wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, X.sup.1, X.sup.2, X.sup.3, X.sup.4, A, Y and n are as described in the specification, pharmaceutical compositions containing them and intermediates used in their manufacture. More particularly, the compounds of the invention are motilin receptor antagonists useful for the treatment of associated conditions and disorders such as gastrointestinal reflux disorders, eating disorders leading to obesity and irritable bowel syndrome.

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Patent Owner(s)

Patent OwnerAddress
ORTHO-MCNEIL PHARMACEUTICAL INCU S ROUTE 202 RARITAN NJ 08869

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Johnson, Sigmond G Flemington, NJ 12 68
Rivero, Ralph A North Wales, PA 46 537

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