Large conductance calcium-activated k channel opener
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United States of America Patent
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Issued Date -
Mar 15, 2007
app pub date -
Oct 15, 2004
filing date -
Oct 17, 2003
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention provides a large conductance calcium-activated K channel opener comprising a compound of the formula (I): wherein R.sup.1 and R.sup.3 are each sulfonamide, carbamoyl, acyl, amino, and the like, m and n are each 0 to 2, R.sup.2 and R.sup.4 are each cyano, nitro, hydroxyl, an alkoxy, a halogen, or an alkyl, Ring A is benzene or a heterocyclic ring, Ring B is benzene, a heterocyclic ring, a cycloalkane etc, and Ring Q is pyrazole or isoxazole, or a pharmaceutically acceptable salt thereof as an active ingredient.
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