Novel oligonucleotide compositions and probe sequences useful for detection and analysis of microRNAS and their target mRNAS
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United States of America Patent
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Issued Date -
Mar 22, 2007
app pub date -
Mar 23, 2006
filing date -
Mar 23, 2005
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Abstract
The invention relates to ribonucleic acids and oligonucleotide probes useful for detection and analysis of microRNAs and their target mRNAs, as well as small interfering RNAs (siRNAs). The invention furthermore relates to oligonucleotide probes for detection and analysis of other non-coding RNAs, mRNAs, mRNA splice variants, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g. alterations associated with human disease, such as cancer.
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