Methods to synthesize indoles as precursors for pharmaceuticals
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United States of America Patent
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Issued Date -
Mar 22, 2007
app pub date -
Aug 21, 2006
filing date -
Aug 19, 2005
priority date (Note) -
Abandoned
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Abstract
The invention provides improved methods for the synthesis of indoles, especially useful for making indoles having an ester or amide group at C-5. The methods involve cyclization of a protected ortho-acetylene-substituted aniline derivative to produce an indole.
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