Crystalline forms of (+)- and (-) erythro-mefloquine hydrochloride
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Dec 17, 2004
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Dec 17, 2003
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Abstract
(+)- or (-)-erythro-Mefloquine hydrochloride can exist in four crystalline forms A, B, C and D, whereby form A is the most stable form. Form A can be directly produced in morphological forms like thick columns, cuboids, cubes and cube-like forms, which can be easily handled during processing and formulation. (+)- or (-)-eroryth-Mefloquine hydrochloride also forms solvates with acetone, methyl ethyl ketone and tetrahydrofuran.
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