Method for high throughput volumes in the fractionation of bio-molecules by chromatographic systems
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United States of America Patent
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Issued Date -
Apr 26, 2007
app pub date -
Mar 19, 2004
filing date -
Mar 21, 2003
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Abstract
The present invention provides industrial scale expanded bed adsorption process for fractionation and isolation of bio-molecules from fluids, preferably proteins from milk and whey, in a cost-effective manner. This is accomplished by operating the expanded bed column at high temperatures of at last 40.degree. C., combined with applying flow rates greater than 1.500 cm/hour.
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