Orally administrable extended release pellet and tablet formulations of a highly water soluble compound
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United States of America Patent
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Issued Date -
Jun 14, 2007
app pub date -
Dec 8, 2005
filing date -
Dec 8, 2005
priority date (Note) -
Abandoned
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Abstract
Pharmaceutical compositions comprising an extended release formulation of active compounds effective in the treatment of various pathological conditions are provided. More particularly, the invention provides methods of making and using extended release formulations comprising active compounds that present formulation challenges such as short biological half-life, instability, highly water soluble and/or high dose requirements. Specifically, orally administrable extended release pellet and tablet formulations of isovaleramide are preferred.
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