Hiv-dependent expression constructs and uses therefor

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United States of America Patent

APP PUB NO 20070134767A1
SERIAL NO

10574031

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides nucleic acid molecules comprising expressible sequences, including reporter genes and therapeutic genes, whose expression is dependent on the presence of both HIV Tat and Rev proteins. Further provided are methods for detecting HIV, method for identifying compounds that can inhibit HIV infection and/or gene expression, methods for killing HIV-infected cells, and methods of treating HIV-infected subjects.

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Patent Owner(s)

Patent OwnerAddress
GEORGE MASON INTELLECTUAL PROPERTIES INC4400 UNIVERSITY DRIVE OFFICE OF TECHNOLOGY TRANSFER MSN-5G5 FAIRFAX VA 22030

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Marsh, Jon W Bethesda, MD 1 1
Wu, Yuntao Manassas, VA 35 51

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