Selective isolation and concentration of nucleic acids from complex samples
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United States of America Patent
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Issued Date -
Jul 5, 2007
app pub date -
Jun 23, 2006
filing date -
Jun 23, 2005
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Abstract
The present invention provides methods for detecting a target nucleic acid molecule in a sample that comprises nucleic acid molecules of higher biological complexity than that of amplified nucleic acid molecules in a complex environment containing numerous non-nucleic acid components. In particular, the present invention provides methods and probes for isolating DNA with detergents and detecting a single nucleotide polymorphism (SNP) in a complex sample that comprises numerous non-nucleic acid components and nucleic acid molecules of higher biological complexity than that of amplified nucleic acid molecules.
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