Osteogenic proteins

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United States of America Patent

SERIAL NO

11643552

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Abstract

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Disclosed are (1) osteogenic devices comprising a matrix containing substantially pure natural-sourced mammalian osteogenic protein; (2) DNA and amino acid sequences for novel polypeptide chains useful as subunits of dimeric osteogenic proteins; (3) vectors carrying sequences encoding these novel polypeptide chains and host cells transfected with these vectors; (4) methods of producing these polypeptide chains using recombinant DNA technology; (5) antibodies specific for these novel polypeptide chains; (6) osteogenic devices comprising these recombinantly produced proteins in association with an appropriate carrier matrix; and (7) methods of using the osteogenic devices to mimic the natural course of endochondral bone formation in mammals.

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Patent Owner(s)

Patent OwnerAddress
STRYKER CORPORATION2825 AIRVIEW BOULEVARD KALAMAZOO MI 49002

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kuberasampath, Thangavel Holliston, MA 76 2452
Oppermann, Hermann Medway, MA 112 3780
Ozkaynak, Engin Milford, MA 58 1378
Pang, Roy HL Etna, NH 13 107
Rueger, David C Southborough, MA 109 3082

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