Composition for ultrasound therapy and pharmaceutical liquid composition containing the same
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United States of America Patent
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Issued Date -
Aug 9, 2007
app pub date -
Jan 5, 2007
filing date -
Jan 6, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention provides pharmaceutical liquid compositions, comprising a liquid, a prodrug, and a large quantity of microbubbles formed by a gas dispersed in the liquid, the microbubbles having a diameter between about 0.1 .mu.m and 100 .mu.m, wherein a majority of the prodrug is present outside the microbubbles. The compositions can be used for an ultrasound therapy or for enhancing effects of an ultrasound therapy. The compositions are also useful for enhancing the therapeutic effect of a prodrug, and for enhancing the therapeutic effect of ultrasound.
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