Huvastatin and its preparation and formulation comprising the huvastatin
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United States of America Patent
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Issued Date -
Aug 9, 2007
app pub date -
Nov 29, 2004
filing date -
Dec 1, 2003
priority date (Note) -
Abandoned
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Abstract
The invention relates to statin compounds, and it discloses novel small molecule compounds, i.e., huvastatins, which are classified into I, II, and III. The invention also provides the preparation methods thereof and the formulations comprising the huvastatin as active ingredient. The present compounds can be used at lower dosage compared to the existing statin compounds, and also can help to control the desired blood lipid levels of the patients with hyperlipidemia. Huvastatin of the invention exhibits suitable hydrophilicity, strong potency and therapeutical effect for reducing lipid levels, and lower dosage.
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