Flux limiting membrane for intravenous amperometric biosensor
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United States of America Patent
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Issued Date -
Aug 30, 2007
app pub date -
Feb 23, 2007
filing date -
Feb 27, 2006
priority date (Note) -
Abandoned
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Abstract
A flux limiting layer for an intravenous amperometric biosensor is formed on a substrate to limit a diffusion rate of an analyte from blood to an enzyme electrode. The layer may be formed from ethylene vinylacetate (EVA) dissolved in a solvent such as paraxylene, spray-coated to cover a portion of the electrode, and cured to seal the electrode to the substrate. In a glucose sensor having glucose oxidase disposed on the electrode, thickness and concentration of the EVA layer are optimized to promote a linear output of electrode current as a function of blood glucose concentration.
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