Silicone based emulsions for topical drug delivery
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United States of America Patent
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Issued Date -
Sep 6, 2007
app pub date -
Jan 30, 2007
filing date -
Mar 3, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A water-in-oil emulsion is provided in which the lipophilic phase of the emulsion contains a silicone fluid and an emulsifier, a hydrophilic phase, and a pharmaceutically active compound. The active pharmaceutical ingredient is dissolved or dispersed in the emulsion and is partitioned in the emulsion so that all or a portion of the amount of the chemical compound dissolved or dispersed in the emulsion is dissolved or dispersed in the aqueous phase of the emulsion. The emulsion of the invention provides increased penetration into skin of the chemical compound dissolved or dispersed in the aqueous phase.
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