COMPOSITION AND METHOD OF USE THEREOF
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United States of America Patent
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Issued Date -
Sep 27, 2007
app pub date -
Dec 28, 2006
filing date -
Jan 5, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A pharmaceutical composition comprises (a) metronidazole in an antibacterially effective amount; and (b) an antifungal agent in an antifungally effective amount, illustratively comprising butoconazole or a pharmaceutically acceptable salt or ester thereof. The composition is adapted for application in a unit dose amount to a vulvovaginal surface and has at least one nonlipoidal internal phase and at least one lipoidal external phase that is bioadhesive to the vulvovaginal surface. The composition is useful for administration to a vulvovaginal surface to treat a mixed bacterial vaginosis and vulvovaginal candidiasis infection.
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