Synchronization of vagus nerve stimulation with the cardiac cycle of a patient
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United States of America Patent
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Jul 10, 2012
Grant Date -
Oct 4, 2007
app pub date -
Mar 29, 2007
filing date -
Mar 29, 2006
priority date (Note) -
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Abstract
Methods, systems, and apparatus for treating a medical condition of a patient, involving detecting a physiological cycle or cycles of the patient and applying an electrical signal to a portion of the patient's vagus nerve through an electrode at a selected point in the physiological cycle(s). The physiological cycle can be the cardiac and/or respiratory cycle. The selected point can be a point in the cardiac cycle correlated with increased afferent conduction on the vagus nerve, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during inspiration by the patient. The selected point can be a point in the cardiac cycle when said applying increases heart rate variability, such as a point from about 10 msec to about 800 msec after an R-wave of the patient's ECG, optionally during expiration by the patient.
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