Process for preparing tetrahydrobiopterin and analogs of tetrahydrobiopterin
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United States of America Patent
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Jun 8, 2010
Grant Date -
Oct 18, 2007
app pub date -
Nov 17, 2004
filing date -
Nov 17, 2003
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Abstract
Process for the preparation of tetrahydrobiopterin from neopterin and/or 6-substituted pterins with an improved yield and a high stereoselectivity. Also disclosed herein are novel individual intermediates prepared in the preparation of tetrahydrobiopterin, such as selectively protected neopterin useful for the preparation of tetrahydrobiopterin.
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