Chimeric Bacteriophages, Chimeric Phage-Like Particles, and Chimeric Phage Ghost Particles, Methods for Their Production and Use

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United States of America Patent

APP PUB NO 20070248573A1
SERIAL NO

11663209

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The objective of the present invention is to provide chimeric phage-derived particles, that may be used as safe food grade vehicles to for presenting various factors (e.g. antigens, virulence proteins, receptors, ligands, etc.) for living cells. In addition to at least one normal phage or virus component the particles comprise at least one additional factor that is not encoded by the genetic material of the chimeric particle. Applications for such particles include, but are not limited to, vaccine development, pathogen neutralization, chemical binding and/or neutralization (e.g. toxins), and competitive exclusion. In addition, this technology may be used to extend the retention time of phage particles during phage therapy and/or specifically target a given particle for a biofilm.

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Patent Owner(s)

Patent OwnerAddress
CHR HANSEN A/SBOEGE ALLE 10-12 HOERSHOLM 2970

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sturino, Joseph Milwaukee, WI 2 10

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