Differentiation of pluripotent stem cells to definitive endoderm lineage
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United States of America Patent
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Jun 3, 2014
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Apr 18, 2007
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Apr 28, 2006
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Abstract
The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer.
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