Epimerisation of Allylic Alcohols
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United States of America Patent
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Issued Date -
Nov 1, 2007
app pub date -
Aug 22, 2005
filing date -
Sep 1, 2004
priority date (Note) -
Abandoned
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Abstract
The present invention relates to processes for epimerising alcohols of compounds having a hydroxyl substituent on an asymmetric allylic carbon, such as compounds useful for the synthesis of vitamin D analogues where the epimeric hydroxyl substituent is at the 24 position. The Invention further relates to methods of producing intermediates useful for the synthesis of calcipotriol by said epimerisation processes.
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