Nanoelectronic Detection of Biomolecules Employing Analyte Amplification and Reporters
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United States of America Patent
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Apr 2, 2007
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Aug 24, 2004
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Abstract
Methods of detection of biomolecules are described, including methods of amplification of analyte target species and target reporters by analyte-triggered action of an enzyme such a nuclease, polymerase, and the like. Amplified target species (e.g., amplicons and reporters) are detectable by several embodiments of nanoelectronic sensors having aspects of the invention, and by alternative convention biomolecule detection methods.
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