Pufa polyketide synthase systems and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7803620
APP PUB NO 20070266455A1
SERIAL NO

11689453

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Abstract

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, and biologically active fragments and homologues thereof. More particularly, this invention relates to nucleic acids encoding such PUFA PKS systems, to proteins and domains thereof that comprise such PUFA PKS systems, to genetically modified organisms (plants and microorganisms) comprising such PUFA PKS systems, and to methods of making and using the PUFA PKS systems disclosed herein. This invention also relates to genetically modified plants and microorganisms and methods to efficiently produce lipids enriched in various polyunsaturated fatty acids (PUFAs) as well as other bioactive molecules by manipulation of a PUFA polyketide synthase (PKS) system.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
DSM IP ASSETS B.V.6411 TE HEERLEN1181

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Metz, James G Longmont, US 80 2691
Weaver, Craig A Boulder, US 49 1651
Zirkle, Ross Longmont, US 42 769

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
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THE UNIVERSITY OF YORK (1)
2005/0164,192 Transgenic plants expressing enzymes involved in fatty acid biosynthesis 138 2005
 
E. I. DU PONT DE NEMOURS AND COMPANY (2)
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ABBOTT LABORATORIES (2)
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MARTEK BIOSCIENCES CORPORATION (2)
2008/0038,378 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 39 2007
2008/0038,379 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 48 2007
 
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
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Biotica Technology Limited (1)
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ROCHE DIAGNOSTICS GMBH (1)
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SUPERMEDIA LLC (1)
2008/0044,870 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
 
IACR-ROTHAMSTED (1)
2005/0089,865 Delta 6 desaturases from primulaceae, expressing plants and pufa-containing oils 70 2004
 
KOSAN BIOSCIENCES, INC. (1)
2004/0005,672 Heterologous production of polyketides 55 2003
 
MONSANTO COMPANY (1)
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DSM IP ASSETS B.V. (50)
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7247461 Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof 46 2002
7214853 Schizochytrium PKS genes 62 2002
7211418 PUFA polyketide synthase systems and uses thereof 72 2004
7217856 PUFA polyketide synthase systems and uses thereof 70 2004
7256022 Pufa polyketide synthase systems and uses thereof 50 2005
7256023 PUFA polyketide synthase systems and uses thereof 52 2005
7259295 PUFA polyketide synthase systems and uses thereof 50 2005
7271315 PUFA polyketide synthase systems and uses thereof 69 2006
2007/0256,146 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 45 2007
2007/0244,192 PLANT SEED OILS CONTAINING POLYUNSATURATED FATTY ACIDS 71 2007
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2008/0026,434 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0026,435 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0026,436 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0026,437 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0032,296 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 26 2007
2008/0026,438 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0026,439 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 37 2007
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2008/0032,351 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 38 2007
2008/0038,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0022,422 CHIMERIC PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 67 2007
2008/0148,433 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0038,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 37 2007
2008/0038,792 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 36 2007
2008/0044,867 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 38 2007
2008/0038,793 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0038,794 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,795 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0038,796 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0038,797 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0040,822 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 49 2007
2008/0044,868 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,869 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0044,871 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 45 2007
2008/0044,872 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0044,873 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 44 2007
2008/0050,790 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 42 2007
2008/0032,338 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0032,367 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0032,368 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 26 2007
2008/0032,369 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0038,798 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0038,799 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0044,874 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
2008/0050,791 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 28 2007
 
SAGAMI CHEMICAL RESEARCH CENTER (3)
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MONSANTO COMPANY (1)
6140486 Production of polyunsaturated fatty acids by expression of polyketide-like synthesis genes in plants 105 1998
 
BIORIGINAL FOOD & SCIENCE CORP. (1)
7087432 Fad4, Fad5, Fad5-2 and Fad6, novel fatty acid desaturase family members and uses thereof 65 2001
 
SEMBIOSYS GENETICS INC. (1)
2007/0245,431 POLYUNSATURATED FATTY ACID PRODUCTION IN HETEROLOGOUS ORGANISMS USING PUFA POLYKETIDE SYNTHASE SYSTEMS 76 2007
 
WASHINGTON STATE UNIVERSITY (1)
2004/0010,817 Plant acyl-CoA synthetases 49 2003
 
Miami University, an Ohio corporation (1)
2004/0139,498 Fatty acid elongase 3-ketoacyl CoA synthase polypeptides 48 2004
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
9580758 System and method for the detection and treatment of infection by a microbial agent associated with HIV infection 0 2014
 
DSM IP ASSETS B.V. (5)
8940884 Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof 0 2010
* 2010/0266,564 Polyunsaturated Fatty Acid Synthase Nucleic Acid Molecules and Polypeptides, Compositions, and Methods of Making and Uses Thereof 6 2010
* 2011/0167,508 PUFA POLYKETIDE SYNTHASE SYSTEMS AND USES THEREOF 5 2010
8309796 Chimeric PUFA polyketide synthase systems and uses thereof 0 2011
8859855 Chimeric PUFA polyketide synthase systems and uses thereof 0 2012
* Cited By Examiner

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