Haplotype Markers And Methods Of Using The Same To Determine Response To Treatment
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United States of America Patent
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Issued Date -
Jan 24, 2008
app pub date -
May 4, 2005
filing date -
May 4, 2004
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Abstract
The present invention relates to methods for diagnosing or predicting responsiveness to treatment, such as Alefacept, by determining the presence of a nucleotide at one or more polymorphic sites within a haplotype marker. The present invention identifies multiple haplotypes that are associated with response to Alefacept. The haplotype markers identified by the present invention and methods of the invention can be particularly useful for diagnosing or predicting susceptibility to skin diseases, such as Psoriasis.
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