Tailored Treatment Suitable for Different Forms of Mastocytosis
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United States of America Patent
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Issued Date -
Jan 31, 2008
app pub date -
Feb 27, 2004
filing date -
Feb 27, 2003
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Abstract
The present invention relates to a method for a tailored treatment of mastocytosis comprising a) assessing whether or not a c-kit mutation at position 816 is detected in a sample of a patient and b) administering a specific 816 mutant c-kit inhibitor in case a mutation is detected in step a) or an inhibitor displaying efficacy on c-kit wild in case no mutation is detected in step a). The invention is more particularly suited 10 for treating category II, III and IV mastocytosis.
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