Methods of treating ankylosing spondylitis using anti-TNF antibodies and peptides of human tumor necrosis factor
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United States of America Patent
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app pub date -
Mar 2, 2007
filing date -
Jan 8, 2001
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Abstract
Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-.alpha. (TNF.alpha.) and are useful in vivo diagnosis and therapy of a number of TNF.alpha.-mediated pathologies and conditions, including ankylosing spondylitis, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
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