Hydrogel for an intravenous amperometric biosensor
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United States of America Patent
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Issued Date -
Feb 7, 2008
app pub date -
Feb 20, 2007
filing date -
Feb 27, 2006
priority date (Note) -
Abandoned
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Abstract
A hydrogel for an intravenous amperometric biosensor is formed on an electrode from a matrix of chitosan and a cross-linking agent, such as genipin to immobilize a reactive agent such as glucose oxidase. The matrix may also function as a rate-limiting layer to selectively control diffusion to the reactive agent. A method for forming the hydrogel on an electrode for immobilizing a reactive agent may include dissolving chitosan in an acidic solution, adding the reactive agent, applying solution to the electrode surface, curing the solution to a solid film, and immersing the same in a genipin buffer.
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