Humanized monoclonal antibody 31.1 as an anticancer agent
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United States of America Patent
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app pub date -
Dec 22, 2006
filing date -
Jun 30, 2004
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Abstract
The present invention is directed to a CHO cell expression system for high level expression of a chimeric 31.1 monoclonal antibody specific for a human carcinoma-associated protein antigen. The present invention also provides a pharmaceutical composition comprising chimeric 31.1 monoclonal antibody derived from the CHO cells of the invention for use in immunotherapy or immunodiagnosis.
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