Stabilization of lorazepam
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United States of America Patent
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Issued Date -
Feb 7, 2008
app pub date -
Aug 2, 2007
filing date -
Aug 4, 2006
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
This invention relates to orally disintegrable, lorazepam-containing dosage forms which are storage stable and disintegrable within about 90 seconds or less. In one embodiment, there is provided a storage stable, orally disintegrable dosage form comprising: protected lorazepam particles comprising lorazepam and polymeric material having a glass transition temperature of about 65.degree. C. or above. Also disclosed is a method of producing a storage stable lorazepam containing tablet.
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