Systems, methods, and compositions for mixing and applying lyophilized biomaterials
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United States of America Patent
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app pub date -
Oct 9, 2007
filing date -
Nov 6, 1998
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Abandoned
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Abstract
A method of treating tissue lyophilizes a biocompatible polymer having a functionality equal to or greater than three. The method provides a protein solution. The method mixes the protein solution with the lyophilized polymer to reconstitute the polymer and form a mixture, wherein, upon mixing, the protein solution and the polymer cross-link to form a material composition. The method applies the material composition to a tissue region. The biocompatible polymer can comprise, e.g., poly(ethylene glycol) PEG. The protein solution can comprise, e.g., albumin.
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