Medical Devices for Delivering a Therapeutic Agent and Method of Preparation
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United States of America Patent
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app pub date -
Oct 30, 2007
filing date -
Apr 26, 1993
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Abandoned
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Abstract
A device useful for localized delivery of a therapeutic agent includes a structure including a porous polymeric material and an elutable therapeutic agent in the form of a solid, gel, or neat liquid, which is dispersed in at least a portion of the porous polymeric material. A method for making a medical device having a blood-contacting surface involves: providing a structure comprising a porous material; contacting the structure comprising a porous material with a concentrating agent to disperse the concentrating agent throughout at least a portion of the porous material; contacting the structure comprising a porous material and the concentrating agent with a solution of a therapeutic agent; and removing the therapeutic agent from solution within the porous material at the locations of the concentrating agent. Another method involves multiple immersion steps without the use of a concentrating agent.
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