Abuse-resistant controlled-release opioid dosage form
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United States of America Patent
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Issued Date -
Mar 20, 2008
app pub date -
Sep 14, 2007
filing date -
May 11, 2001
priority date (Note) -
Abandoned
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Abstract
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress the euphoric effect of the opioid, if the combination were crushed to break the controlled release properties causing the opioid and opioid antagonist to be released as an immediate release product as a single dose. The controlled release nature of the tablet prevents the accumulation of orally effective amounts of opioid antagonist when taken normally. The opioid antagonist is contained in a controlled-release matrix and released, over time, with the opioid.
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