Gene and protein expression profiles associated with the therapeutic efficacy of irinotecan
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United States of America Patent
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Issued Date -
Mar 27, 2008
app pub date -
Sep 21, 2007
filing date -
Sep 21, 2006
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Abstract
The present invention includes gene and protein expression profiles indicative of whether a cancer patient is likely to respond to treatment with irinotecan. By identifying such responsiveness, a treatment provider may determine in advance those patients who would benefit from such treatment, as well as identify alternative therapies for non-responders. The present invention further provide methods of using the gene and/or protein expression profiles and assays for identifying the presence of a gene and/or protein expression profile in a patient sample.
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