Invertebrate-Derived Gonadotropic Hormone and its Synthesis

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United States of America Patent

APP PUB NO 20080096251A1
SERIAL NO

11661140

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The structure of gonadotropic hormone of an invertebrate (Asterina pectinifera) was elucidated. The gonadotropic hormone is a peptide with molecular weight 4500 to 4900 composed of two subunits, wherein the structure of the protein has the structure bound by SS bridges formed between SH residues of cysteines contained in the subunits. Mixing and oxidizing these two subunits after their synthesis enables to give a peptide (gonadotropic hormone) with gonad-stimulating activity.

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Patent Owner(s)

Patent OwnerAddress
TEIKYO UNIVERSITY2-11-1 KAGA ITABASHI-KU TOKYO 173-8605
INTER-UNIVERSITY RESEARCH INSITUTE CORPORATION NATIONAL INSTITUTES OF NATURAL SCIENCES2-21-1 OSAWA MITAKA-SHI TOKYO 1818588
NATIONAL UNIVERSITY CORPORATIO NAGOYA UNIVERSITY1 FUROCHO CHIKUSA-KU NAGOYA-SHI AICHI 4648601

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Isobe, Minoru Aichi, JP 46 839
Mita, Masatoshi Tokyo, JP 1 0
Nagahama, Yoshitaka Aichi, JP 3 0
Yoshikuni, Michiyasu Aichi, JP 1 0

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