5-Carboxamido Substituted Thiazole Derivatives that Interact With Ion Channels, In Particular With Ion Channels From the Kv Family
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United States of America Patent
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Issued Date -
May 29, 2008
app pub date -
Dec 1, 2005
filing date -
Dec 1, 2004
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Abandoned
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Abstract
The present invention relates to compounds that interact with ion channels. In particular, the invention relates to compounds having the structural Formula having the structural Formula I, II, III or IV, stereoisomers, tautomers, racemics, prodrugs, metabolites thereof, or a pharmaceutically acceptable salt and/or solvate thereof, wherein X, Y.sup.1, Y.sup.2, R.sup.1, n, R.sup.3, R.sup.8, R.sup.9, R.sup.10, L.sup.1, L.sup.2, Ar.sup.1 and Ar.sup.2 are defined in claim 1. The invention also relates to methods for preparing said compounds, to pharmaceutical compositions comprising said compounds, and to the use of said compounds in methods for treatment of the human and animal body.
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