Recombiant Protein Expression Systems and Applications Thereof

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United States of America Patent

APP PUB NO 20080131444A1
SERIAL NO

11666059

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to a transitory expression system of recombinant proteins in a plant, characterized in that it comprises a viral expression vector comprising a ubiquitous constitutive promoter upstream from a gene of interest or a reporter gene placed downstream from the viral vector or a gene that is adapted for expression of eucaryotic genes or a construction that comprises a gene of interest placed downstream from a constitutive promoter, wherein said constructions are complemented by a construction which also comprises the gene P1 which is placed downstream from the ubiquitous constitutive promoter and which suppresses the silencing of the virus of the yellow variegation of rice (RYMV, Rice Yellow Mottle Virus). Application: production of proteins of therapeutic interest.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT DE RECHERCHE POUR LE DEVELOPMENT (IRD)213 RUE LA FAYETTE PARIS CEDEX 10 F-75480

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brugidou, Christophe Pignan, FR 5 3
Lemesre, Jean-Loup Montpellier, FR 15 17
Piron, Florence Savigny sur Orge, FR 1 1
Reyser, Martine Saint-Bauzille De Putois, FR 1 1
Sire, Christelle Barcelona, ES 2 3

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