Engineered cleavage half-domains

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United States of America Patent

APP PUB NO 20080131962A1
SERIAL NO

11805850

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are engineered cleavage half-domains; fusion polypeptides comprising these engineered cleavage half-domains; polynucleotides encoding the engineered cleavage half-domains and fusion proteins; and cells comprising said polynucleotides and/or fusion proteins. Also described are methods of using these polypeptides and polynucleotides, for example for targeted cleavage of a genomic sequence.

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Patent Owner(s)

Patent OwnerAddress
SANGAMO THERAPEUTICS INC7000 MARINA BOULEVARD BRISBANE CA 94005

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Miller, Jeffrey C Pleasanton, CA 103 3609

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