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Abstract

A filtration system comprising a plurality of filters. Each filter defines a respective filter flowpath extending adjacent a respective filtration medium for tangential filtration by the filtration medium of fluid passing through the filter flowpath. The system also comprises a manifold connected to each filter, the system being selectively operable in a first state in which the manifold and the filter flowpaths form part of a first continuous flowpath around which fluid circulates passing in parallel through the filter flowpaths and a second state in which fluid circulates around a second continuous flowpath including the filter flowpath of at least one but not all of the filters, the second continuous flowpath having a lower volume than the first continuous flowpath and fluid passing into the second continuous flowpath from the manifold responsive to tangential filtration in the second state.

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