Semi-synthesis and isolation of taxane intermediates from a mixture of taxanes
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United States of America Patent
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Nov 23, 2010
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Apr 22, 2005
filing date -
Apr 23, 2004
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Abstract
A process is provided for the semi-synthesis and isolation of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis and isolation of 10-deacetylbaccatin III, the semi-synthesis of a mixture of 10-deacetylbaccatin III and baccatin III, and protected derivatives thereof, from a mixture of taxanes.
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