Polynucleotides, Polypeptides and Method for Screening for Useful Dog Candidates
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United States of America Patent
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app pub date -
Jul 26, 2007
filing date -
Dec 24, 2002
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Abandoned
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Abstract
A method for screening for useful dog candidates comprises a step of investigating the genotype of the allele in exon 1 or intron 2 of dog dopamine receptor D4 gene, and a step of selecting a dog with genetic aptitudes beneficial to people by making the selection based on that genotype. The step of investigating the genotype comprises a step of amplifying the allele using a pair of PCR primers that bond in the vicinity of both terminals of the allele, and a step of determining the genotype of the allele based on the lengths of the PCR products obtained by that step. A dog having the nucleotide sequence represented by SEQ ID NO: 5 for at least one of the alleles in exon 1, or a dog having the nucleotide sequence represented by SEQ ID NO: 9 for at least one of the alleles in intron 2, is useful as a seeing-eye dog or other service dog.
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