Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid
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United States of America Patent
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Issued Date -
Jul 24, 2008
app pub date -
Sep 21, 2007
filing date -
Sep 28, 2006
priority date (Note) -
Abandoned
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Abstract
A controlled release dosage form containing lercanidipine, or a salt thereof, a performance-enhancing acid, and at least one other pharmaceutical excipient exhibits enhanced in vitro dissolution of lercanidipine, enhanced storage stability based upon the reduced degradation of lercanidipine, and/or enhanced in vivo bioavailability of lercanidipine as compared to an otherwise similar controlled release dosage form excluding the performance-enhancing acid but containing the same amount of lercanidipine.
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