Optical determination of ph and glucose
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United States of America Patent
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Jul 6, 2010
Grant Date -
Aug 7, 2008
app pub date -
Feb 6, 2007
filing date -
Feb 6, 2007
priority date (Note) -
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Abstract
Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
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