Method for treating pulmonary disease states in mammals by altering indigenous in vivo levels of nitric oxide
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United States of America Patent
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Jan 22, 2008
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Jul 25, 2002
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Abstract
The present invention provides a method for treating a pulmonary disease state in mammals by protecting indigenous in vivo levels of nitric oxide in mammalian cells comprising contacting the mammalian cells with a therapeutically effective amount of a nitric oxide mediator, wherein the nitric oxide mediator is selected from the group consisting of .alpha.-keto acids having four or more carbon atoms, precursors of .alpha.-keto acids having four or more carbon atoms, and the salts thereof.
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