Abuse-deterrent multi-layer pharmaceutical composition comprising an opioid antagonist and an opioid agonist
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United States of America Patent
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Apr 17, 2012
Grant Date -
Sep 25, 2008
app pub date -
Jun 19, 2007
filing date -
Jun 19, 2006
priority date (Note) -
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Abstract
Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one sequestering polymer are all components of a single unit, and wherein the seal coat forms a layer physically separating the antagonist from the agonist from one another. Methods for manufacturing such a pharmaceutical composition are also provided.
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