Antibody composition-producing cell in which enzyme expression is inhibited by RNAi
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United States of America Patent
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Dec 7, 2010
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Apr 1, 2008
filing date -
Oct 6, 2000
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Abstract
The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, wherein the expression of GDP-mannose 4,6-dehydrogenase is inhibited by RNA interference.
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